worldwide virus infections

chicken pox causative agent
varicella zooster virus
VZV
VZV etiology
dsDNA
polyhedral capsule
envelope
large
vzv reservoir
infected humans
vzv transmission
droplet
direct
fomites
vzv clinical
incubation 10-23 days
vesicular rash, fever, headache, fatigue, sore throat, anorexia, irritability, itching
shingles clinical
vesicular pustular rash along a nerve from one dorsal root
pain
vzv diagnosis
clinical
vzv treatment
supportive care
antihistamines, calomine lotion, antipyretics, fluids
mono causative agent
epstein barr virus
mono eitology
dsDNA
polyhedral capsid
envelope
large
mono reservoir
infected humans
mono transmission
direct, fomites, requires saliva exchange
mono clinical
children: asymptomatic
adults: 4-7 weeks incubation
fever, tonsilitis, lymphoadenopathy, fatigue
mono pathogenesis
entry: directed contact with saliva
attachment: oropharynx epithelium, b lymphocytes
avoid: intracellular, latent provirus formation
damage: immunological civil war – activated t cells attack infected b cells
exit: shed from cells infected cells in salvia
mono diagnosis
atypical lymphocytes in blood
mono treatment
supportive care
bed rest, fever treatment, sore throat treat. fluids
mono prevention
difficult
risk decreased by frequent hand washing
measles causative agent
measles virus
measles etiology
ssRNA negative
helical capsid
enveloped
measles reservoir
infected humans
measles transmission
airbourne, droplet, fomite, direct
measles clinical
incubation 10-14 days
cough, conjunctivitis, fever, Koplik spots, macular rash
measles pathogenesis
entry: respiratory
attach: mucosa, alveolar macrophages
avoid: intracellular
overcome: destroys t cells
damage: syncytia formation, inflammation
exit: respiratory route
measles diagnosis
koplick spots
macular rash
measles treatment
supportive care
fever, fluids, oxygen and hospitalization
measles prevention
MMR vaccine
very effective
measles prevention
MMR vaccine
very effective
Categories: Microbiology