Yersinia, Francisella, Brucella, and Pasteurella

What are the common characteristics of yersinia, francisella, brucella, and pasteurella?
* gram(-) rod
* zoonotic disease
* very virulent (not pasteurella)
* facultative intracellular organism (not pasteurella)
* treat with aminoglycoside (gentamicin or streptomycin) and/or doxycycline (not pasteurella)
What causes bubonic plague?
Yersinia pestis
What are the virulence factors of Yersinia pestis (resist destruction after phagocytosis)?
* Fraction 1: capsular antigen
* V antigen: protein
* W antigen: lipoprotein
How is tularemia acquired?
by handling rabbits, bites of ticks and deerflies.
Which organism causes tularemia?
Francisella tularensis
Different presentations of tularemia
* ulceroglandular tularemia
* pneumonic tularemia
* oculoglandular tularemia
* typhoidal tularemia (GI tract)

tularemia is similar to bubonic plague, but with much lower mortality

Contact with animal causes infection, no primary skin ulcer, undulant fever (slow rise in temperature during the day). Which organism?
Brucella
Which organism causes the most frequent infection after cat/dog bite?
Pasteurella multocida. Treat with penicillin or doxycycline.
Categories: Microbiology